Personal cancer genomics is discussed by David Haussler, Director of the Center for Biomolecular Science & Engineering at the University of California, Santa Cruz."
David Haussler is the Distinguished Professor of Biomolecular Engineering and Director of the Center for Biomolecular Science & Engineering at the University of California, Santa Cruz.
David Haussler's research lies at the interface of mathematics, computer science, and molecular biology. He develops new statistical and algorithmic methods to explore the molecular function and evolution of the human genome, integrating cross-species comparative and high-throughput genomics data to study gene structure, function, and regulation. He is credited with pioneering the use of hidden Markov models (HMMs), stochastic context-free grammars, and the discriminative kernel method for analyzing DNA, RNA, and protein sequences. He was the first to apply the latter methods to the genome-wide search for gene expression biomarkers in cancer, now a major effort of his laboratory.
David Haussler, Director of the Center for Biomolecular Science & Engineering at the University of California, Santa Cruz, discusses the importance of cancer research and the impact that cancer genomics will have on personal genomics.
Application of engineering principles and equipment to biology and medicine. It includes the development and fabrication of life-support systems for underwater and space exploration, devices for medical treatment (seedialysis, prosthesis), and instruments for monitoring biological processes. Development has been particularly rapid in the area of artificial organs, which culminated in the implantation of an artificial heart into a human being in 1982. Bioengineers also develop equipment that enables humans to maintain body functions in hostile environments, such as the space suits worn by astronauts during extravehicular maneuvers.