Drug Resistance: A Global Challenge to Disease Control

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Partner:: Resources for the Future
Location:: Resources For the Future
Washington, D.C.
Event Date:: 05.05.10
Speakers:: Mark Cohen,; Ramanan Laxminarayan,; Rachel Nugent,; Kevin Outterson
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Summary: Drugs to treat bacterial infections, malaria, and viruses are losing efficacy to pathogen resistance. The past decade has seen significant investment in new tools like drugs and vaccines but relatively little maintenance of existing tools to protect them. Resistance has emerged to artemisinins, the recommended first-line treatment against malaria in most parts of the world, and has also grown rapidly in the case of antibiotics.

How can the world coordinate to address the threat of depleting drug effectiveness? Who bears the cost of decreasing drug effectiveness? And what will the world look like in 10 to 20 years with and without global efforts to contain resistance?

Bio

Mark Cohen

Mark Cohen is Vice President of Research at Resources For the Future.

Ramanan Laxminarayan

Ramanan Laxminarayan is Senior Fellow and Director of the Center for Disease Dynamics, Economics, and Policy at Resources for the Future.

Rachel Nugent

Rachel Nugent is Deputy Director of Global Health at the Center for Global Development.

Kevin Outterson

Kevin Outterson joined the faculty at Boston University Law in Fall 2007. He began teaching as an associate professor of law at West Virginia University in 2002. Before coming to WVU, he was an income partner in the Tax and International groups at McDermott Will & Emery and a capital partner in the Health Law group at Baker Donelson.

He is a graduate of the University of Cambridge (LL.M.) and Northwestern University (B.S. & J.D.). Professor Outterson teaches courses in health care, business law and globalization. His research work focuses on two areas: global pharmaceutical markets and health disparities.

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01.: Drug Resistance: A Global Challenge to Disease Control and Eradication

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Encyclopædia Britannica Article

drug resistance: Property of a disease-causing organism that allows it to withstand drug therapy. In any population of infectious agents, some have a mutation that helps them resist the action of a drug. The drug then kills more of the nonresistant microbes, leaving the mutants without competition to multiply into a resistant strain. This situation is more likely if the drug is not taken properly (e.g., a course of antibiotics not completed, anti-HIV drug doses missed) or not prescribed properly (e.g., an antibiotic given for a viral disease). Resistance factors can also be transferred between species that infect the same body. The overprescription of antibiotics in humans and the addition of antibiotics to animal feed have accelerated the evolution of resistant strains of bacteria, making it increasingly difficult to fight off certain disease-causing organisms.; drug resistance on britannica.com