The Sage Commons is a novel information platform being built by an international partnership of researchers and stakeholders to define the molecular basis of disease and guide the development of effective human therapeutics and diagnostics.
The Sage Commons will be used to integrate diverse molecular mega-data sets, to build predictive bionetworks and to offer advanced tools proven to provide unique new insights into human disease biology. Users will also be contributors that advance the knowledge base and tools through their cumulative participation.
The public access mission of the Sage Commons requires the development of a new strategic and legal framework to protect the rights of contributors while providing widespread access to integrative genomics resources.
Anne Wojcicki is the co-founder of 23andMe. She brings to 23andMe a 10-year background in healthcare investing, focused primarily on biotechnology companies. Wojcicki left the investing world with the hope that she could have a positive impact on research and medicine through 23andMe. From her vantage point, Wojcicki saw a need for creating a way to generate more information - especially more personalized information - so that commercial and academic researchers could better understand and develop new drugs and diagnostics. By encouraging individuals to access and learn about their own genetic information, 23andMe will create a common, standardized resource that has the potential to accelerate drug discovery and bring personalized medicine to the public. (Plus, getting access to her own genetic information and understanding it has always been one of Wojcicki's ambitions.) Wojcicki graduated from Yale University with a B.S. in biology.
U.S. research effort initiated in 1990 by the U.S. Department of Energy and the National Institutes of Health to analyze the DNA of human beings. The project, intended to be completed in 15 years, proposed to identify the chromosomal location of every human gene, to determine each gene's precise chemical structure in order to show its function in health and disease, and to determine the precise sequence of nucleotides of the entire set of genes (the genome). Another project was to address the ethical, legal, and social implications of the information obtained. The information gathered will be the basic reference for research in human biology and will provide fundamental insights into the genetic basis of human disease. The new technologies developed in the course of the project will be applicable in numerous biomedical fields. In 2000 the government and the private corporation Celera Genomics jointly announced that the project had been virtually completed, five years ahead of schedule.
I am interested in collaborating with 23andMe. As founder of Carolyn's The DNA Diet I have experience in this space and am thrilled that the tipping point appears to be here for 4P health.